A Natural Treatment for Chronic Pain using Palmitoylethanolamide

Everyone feels pain because this is the body’s way of communicating that something is wrong. Chronic pain can cause discomfort to an individual because the body keeps hurting. The best method to deal with chronic pain is to consult a doctor to get treatment. In your quest for treatment of chronic pain, doctors have recommended the use of Palmitoylethanolamide (PEA), a natural substance that has shown great results in pain reduction.


Overview of Palmitoylethanolamide (PEA)

The drug belongs to N-acylethanolamines (NAEs) family, and it is also known as palmitoylethanolamine or N-2 hydroxyethyl palmitamide. In the 1950s, Palmitoylethanolamide was recognised as an active anti-inflammatory agent in the yolk of a chicken egg. Its use started in the 1970s where it gained a reputation as a new agent to treat pain and inflammation. Doctors prefer PEA because no serious side effects or drug interactions have been reported.


What is Palmitoylethanolamide (PEA)

The natural substance is an endogenous fatty acid amide that also occurs in foods like milk and eggs. In the U.S., interest in PEA supplements started in the 1990s although it has been used for many decades in Europe, particularly the Netherlands as food for special medical purposes. According to doctors in Australia, Netherlands and Europe, PEA is effective for different types of chronic pain such as visceral pain, neuropathic pain, and inflammatory pain.


Conditions with Proof of Benefits with Palmitoylethanolamide (PEA)

  • Chronic pelvic pain
  • Low back pain such as herniated disc disease, back surgery syndrome, and others
  • Sciatic pain
  • Neuropathic pain-related to stroke and multiple sclerosis
  • Arthritis-osteoarthritis and rheumatoid arthritis
  • Fibromyalgia
  • Carpal tunnel syndrome


How it Works with Pain

Evidence suggests that the pain people feel in their body emanates from neuroinflammation. This is a condition in which several inflammatory cells within the peripheral nervous system (PNS) and central nervous systems (CNS) are activated. It is also characterised by the migration of immune cell into the area with an injury. It is the release of inflammatory molecules in the body that aid in maintaining chronic pain.

As a result, the development of new medications for managing chronic pain focuses on mast cells, glial cells, and the inflammatory cells. The activities of the mast cells and glial cells are suppressed to limit acute pain or chronic pain.


Using PEA Supplements

For patients with chronic pain, the doctor will advise you on how to use PEA. The suggestion is to apply ultra micronised Normast under the tongue for ten days. This will help fill the cells with PEA and afterwards, you are allowed to continue with 600mg tablets twice a day.

The powder is added under the tongue for another ten days in case a 30% decrease in pain is not seen. PEA dose reduce with declines in the pain, but it is highly recommended to operate within the instructions given by the physician. Pain relief is expected within a week but this can take up to 6-8 weeks.


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